Historic Castro AIDS Mural Defaced. You Can Help Restore It Painted in 1998, the mural Hope for the World Cure, at Market and 15th Street in the Castro district, is one of the most potent public art works about the chaos and solidarity of AIDS in San Francisco and worldwde. But a few weeks ago, in late December 2021, approximately one-third of the two-story mural was defaced with graffiti. Restoration will cost an estimated $50,000, according to Precita Eyes' Susan Cervantes, who directed the work's collective creation 25 years ago.